Esperis investigates the effectiveness of Pyrus malus juice by combining in vitro tests on human keratinocytes with in vivo skin hydration measurements on volunteers.
ABSTRACT
There is growing interest in naturally-derived, bioactive cosmetic ingredients, especially those from fruits rich in antioxidants and vitamins. This study investigated the effectiveness of Pyrus malus juice by combining in vitro tests on human keratinocytes with in vivo skin hydration measurements on volunteers. The innovative aspect lies in linking cellular effects to real improvements in skin hydration. In vitro, mitochondrial activity was measured using the MTS assay to assess cell vitality. In vivo, both superficial and deep skin hydration were tracked using Corneometer and MoistureMeterEpiD devices, comparing an active formulation to a placebo over short- and long-term use. Results showed significant increases in cell metabolism and skin hydration following treatment with the active formulation. These findings confirm that Pyrus malus juice delivers measurable benefits for skin vitality and moisture, supporting its use as a valuable ingredient in modern cosmetic products
The cosmetic industry is currently undergoing a significant paradigm shift toward formulations that provide both aesthetic and functional skin benefits. Central to this evolution is the incorporation of plant- and fruit-derived actives with demonstrable biological activity. Fruits, rich in vitamins, antioxidants, and organic acids, have emerged as prime candidates for active cosmetic ingredients due to their capacity to interact with the skin at a cellular level, thereby promoting hydration and regenerative processes.1,2
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