Turning back the ageing clock with snow algae active

ABSTRACT

Environmental factors and lifestyle choices impact our skin deeply, reaching the cells’ DNA and inducing its modification. These so-called ‘epigenetic changes’ create a signature that contributes to the biological age of the cell, which can significantly differ from the chronological one. Through lifestyle choices and targeted interventions, biological age of the skin can be reversed, and skin appearance can be improved. We developed an extract from snow algae that reduces the skin’s biological age by acting on the hallmarks of ageing. These are measurable manifestations of the ageing process inside the cells, revealing the impaired cellular mechanisms that lead to progressive functional decline. In vitro, snow algae extract reversed biological age according to the Horvath clock and it modulated protein levels, bringing them back to a younger profile. The extract consistently showed anti senescence activity, both in vitro as well as clinically, and counteracted UV spots appearance despite sun exposure. Furthermore, it promoted TEWL reduction and showed a moisturizing effect

Living conditions, lifestyle, and environmental exposure significantly influence biological age—the body’s actual physical condition and functionality, independent of the years a person has lived, which is termed the chronological age (Figure 1). The skin, as the body’s primary barrier, is particularly affected by these external and internal factors, which can make one appear much younger or older than their chronological age.