Japanese cosmetic ingredient maker Ichimaru Pharcos has taken the wraps off PeoGlow, a skin tone active derived from an extract of peony roots.
PeoGlow reduces the accumulation of advanced glycation endproducts (AGEs) and blocks the AGE-RAGE (receptors of AGEs) interaction, helping to achieve a more even, radiant skin tone.
AGEs interact with RAGEs, triggering a signaling cascade in melanocytes and keratinocytes that induces both hyperpigmentation and abnormal keratinization—like a domino effect.
One cause of skin dullness is the uneven skin tone, which results from the combination of three colour tones on the skin: brown, due to AGEs; grey, caused by abnormal keratinization; and black, resulting from hyperpigmentation.
This suggests that inhibiting the AGEs-RAGE domino effect could be a simple yet powerful strategy to achieve a more even and radiant skin tone.
Ichimaru Pharcos sought a natural material that inhibits the AGEs-RAGE interaction and discovered that an extract of Peonia albiflora roots has this ability.
As a result, it has launched the natural cosmetic ingredient PeoGlow, which reduces AGEs, skin melanin, skin age spots, and uneven skin tone.
