COVER STORY: The natural bulwark against skin dryness

The skin is the body’s first line of defence, ensured by the barrier function role of the stratum corneum. When this barrier function is altered, the skin progressively loses its defence capabilities, making it vulnerable to dehydration and redness, but also to premature and visible signs of skin ageing. In particular, this is the case for dry skin or skin irritated by the use of certain molecules such as retinol.

Consumers are aware of this essential role of the skin and so are increasingly selecting care products combining protection and comfort. Restructuring active ingredients are therefore strategic solutions.

Silab thus developed a restructuring natural active ingredient that targets the lipid disorders of dry skin: Neolipyl®.

The relationship between modification of the barrier function and the perturbation of lipids is nowadays commonly admitted. From a functional standpoint, the stratum corneum is composed of stacked corneocytes embedded in a lipid matrix in a brick-and-mortar system. This naturally hydrophobic shield prevents water losses from the skin and its efficacy depends on its composition (ceramides, cholesterol and free fatty acids) and on its structure (conformation and organization)

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