The concept of ‘beauty from within‘ continues to redefine the global personal care and wellness industry. At the forefront of this trend is glucosyl hesperidin, an upcycled citrus polyphenol, developed by Nagase Viita, offering scientifically proven benefits for both topical and ingestible beauty applications.
Microcirculation―Traditionally Proven Benefits of Citrus
Hesperidin, a naturally occurring citrus polyphenol, has long been recognized in Asia for promoting healthy blood flow and a warming effect on the body. In traditional Chinese medicine, hesperidin-rich citrus peels, known as Chimpi, were valued for their circulation-boosting properties and used in herbal remedies to support digestion and overall vitality.
Although hesperidin offers notable physiological benefits, its limited water solubility restricted its broader use in cosmetics and functional foods. To overcome this challenge, Nagase Viita developed glucosyl hesperidin by enzymatically combining hesperidin with glucose, dramatically improving its water solubility and expanding its versatility. This innovation has led to two specialized ingredient grades:
- Alpha Glucosyl Hesperidin (AGH) – for cosmetics
- CITRAPEAK™ – for food
Study: Evaluation of Blood Flow Enhancement Following Topical Application of AGH
Methods: A 0.5% AGH cream or placebo was applied on the lips. Changes in microcirculation were measured using laser Doppler blood flowmetry.
Scientifically Proven Efficacy for Glowing Skin
Recent studies demonstrate that both topical and oral applications of glucosyl hesperidin can help reduce dark circles and skin dullness by enhancing blood circulation and inhibiting protein carbonylation and glycation. This dual-action mechanism offers synergistic benefits, promoting a more even tone and a visibly revitalized complexion.
Read the whitepaper for more clinical details.
Beauty That Performs—Responsibly
Beyond its efficacy, glucosyl hesperidin also reflects a commitment to environmental responsibility. It is derived from upcycled citrus fruits, including thinned or fallen fruits, and manufactured through sustainable enzymatic technology. The resulting ingredient is readily biodegradable, minimizing environmental impact and supporting the industry’s shift toward eco-conscious formulations.
In a market that seeks high-performance ingredients with purpose, glucosyl hesperidin stands at the intersection of science and sustainability—advancing beauty and wellness for both people and the planet.
